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Biochemistry news
Mussel-inspired antimicrobial coating protects sanitary fabrics from contamination
Researchers from the UAB and the ICN2 have developed an innovative material to fight against the spread of pathogens, infections and antimicrobial resistance. Inspired by the substances secreted by mussels to adhere to rocks, ...
Biochemistry
Feb 1, 2024
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New drug reveals a key mechanism to overcome resistance to protein degraders
Protein degraders, a novel approach in drug discovery, show promise in tackling diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell's natural ...
Biochemistry
Jan 30, 2024
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6
Chemical biology: A novel approach to synthesize dibenzothiophene s-oxides
Organic compounds in the field of chemistry range from simple hydrocarbons to complex molecules, with diverse functional groups added to the main carbon backbone. These functional groups impart distinct chemical properties ...
Biochemistry
Jan 29, 2024
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14
An enzyme used in laundry detergent can recycle single-use plastics within 24 hours
Scientists at King's College London have developed an innovative solution for recycling single-use bioplastics commonly used in disposable items such as coffee cups and food containers.
Biochemistry
Jan 29, 2024
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373
Enzyme for biocatalysis uses solvent as a substrate
A large number of applications in the chemical industry rely on the molecules NADH or NADPH as fuel. A team led by Professor Dirk Tischler, head of the Microbial Biotechnology working group at Ruhr University Bochum, used ...
Biochemistry
Jan 29, 2024
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14
Molecular simulation AI tool reveals unresolved structure of transporter protein
In a groundbreaking study, researchers have unveiled a previously unknown conformational state of a crucial transporter protein, OxlT, which plays a vital role in preventing kidney stone formation. This discovery, achieved ...
Biochemistry
Jan 29, 2024
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46
New simulation tool advances molecular modeling of biomolecular condensates
A University of Massachusetts Amherst team has made a major advance toward modeling and understanding how intrinsically disordered proteins (IDPs) undergo spontaneous phase separation, an important mechanism of subcellular ...
Biochemistry
Jan 25, 2024
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106
Teaching nature to break man-made chemical bonds
For the first time, scientists have engineered an enzyme that can break stubborn man-made bonds between silicon and carbon that exist in widely-used chemicals known as siloxanes, or silicones. The discovery is a first step ...
Biochemistry
Jan 25, 2024
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14
Team expands research of water droplet interfaces that offer the secret ingredient for building life
R. Graham Cooks, the Henry B. Hass Distinguished Professor of Chemistry, and his postdoctoral researcher Lingqi Qiu have experimental evidence that the key step in protein formation can occur in droplets of pure water, and ...
Biochemistry
Jan 24, 2024
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Chemists use blockchain to simulate more than 4 billion chemical reactions essential to origins of life
Cryptocurrency is usually "mined" through the blockchain by asking a computer to perform a complicated mathematical problem in exchange for tokens of cryptocurrency. But in research appearing in the journal Chem a team of ...
Biochemistry
Jan 24, 2024
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157
LipidOz: New software enables identification of lipid double bond locations
Lipids are a class of biomolecules that play an important role in many cellular processes. Analyses that seek to characterize all lipids in a sample—called lipidomics—are crucial to studying complex biological systems.
Biochemistry
Jan 23, 2024
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Scientists increase the solubility of an effective antidepressant by a factor of 1,600
The anti-anxiety drug diazepam causes side effects: drowsiness, confusion, and nausea. The same applies to the antidepressant amitriptyline. A possible solution to the problem could be a new compound, GML-3. It simultaneously ...
Biochemistry
Jan 22, 2024
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Novel strategy for ultrahigh density copper single atom enzymes developed for tumor therapies
A research group led by Prof. Wang Hui and Prof. Zhang Xin from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences introduced a new strategy to prepare ultrahigh density copper single-atom enzymes ...
Biochemistry
Jan 19, 2024
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New technique provides insight into how proteins involved in cellular processes communicate via extracellular vesicles
One way that cells communicate with one another is through the secretion and uptake of extracellular vesicles (EVs). EVs convey a multitude of cargoes, including proteins, lipids and nucleic acids. Their uptake affects the ...
Biochemistry
Jan 19, 2024
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64
Chemical synthesis: New strategy for skeletal editing on pyridines
A team from the University of Münster has introduced a strategy for converting carbon–nitrogen atom pairs in a frequently used ring-shaped compound into carbon–carbon atom pairs. The method has potential in the quest ...
Biochemistry
Jan 18, 2024
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36
Glowing COVID-19 diagnostic test prototype produces results in one minute
Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? ...
Biochemistry
Jan 17, 2024
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24
Researchers address formulation, manufacturing challenges in obesity, diabetes drugs
Medications such as Ozempic and Mounjaro are composed of molecules called acylated peptides that are designed to circulate in the body and regulate insulin production. This enables adults with type 2 diabetes to take a weekly ...
Biochemistry
Jan 17, 2024
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Molecular 'super-glue' shows promise of cancer drug discovery platform
St. Jude Children's Research Hospital scientists have published their work on SJ3149, a compound with broad activity against many cancer types, particularly acute myeloid leukemia (AML). SJ3149 sticks to the cancer-related ...
Biochemistry
Jan 16, 2024
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61
Chemists find potential new drug for photodynamic cancer therapy
A modern alternative to chemotherapy and radiotherapy is photodynamic therapy. It is used to treat cancer, skin diseases, and infectious diseases. The essence of the method is that light-sensitive substances are introduced ...
Biochemistry
Jan 16, 2024
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New approach to predicting binding properties of PFAS chemicals and human PPARα
Per- and polyfluoroalkyl substances (PFAS) are widely used in various products as water-repellents and stain-resistant coatings. PFAS are called "forever chemicals" due to their exceptional thermal and chemical stability, ...
Biochemistry
Jan 16, 2024
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More news
New research deciphers biomineralization mechanism
Oral peptides: A new era in drug development
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Tracing the evolution of sign languages using computer modeling
Team discovers mechanism that protects tissue after faulty gene expression
Alpine ibex becoming more nocturnal as temperatures rise
Fooled: Herbivorous animals 'led by the nose' to leave plants alone
A physical qubit with built-in error correction
How talin protein maintains intercellular connection while transmitting force
Scientists successfully simulate protein complex that initiates fertilization
Physicists develop highly robust time crystal
